diff --git a/meta-oe/recipes-support/opencv/opencv_4.5.5.bb b/meta-oe/recipes-support/opencv/opencv_4.5.5.bb
index 9627190bd9..a3affa701d 100644
--- a/meta-oe/recipes-support/opencv/opencv_4.5.5.bb
+++ b/meta-oe/recipes-support/opencv/opencv_4.5.5.bb
@@ -100,6 +100,9 @@ EXTRA_OECMAKE = "-DOPENCV_EXTRA_MODULES_PATH=${WORKDIR}/contrib/modules \
     ${@bb.utils.contains("TARGET_CC_ARCH", "-msse4.2", "-DENABLE_SSE=1 -DENABLE_SSE2=1 -DENABLE_SSE3=1 -DENABLE_SSSE3=1 -DENABLE_SSE41=1 -DENABLE_SSE42=1", "", d)} \
 "
 EXTRA_OECMAKE:append:x86 = " -DX86=ON"
+# disable sse4.1 and sse4.2 to fix 32bit build failure
+# https://github.com/opencv/opencv/issues/21597
+EXTRA_OECMAKE:remove:x86 = " -DENABLE_SSE41=1 -DENABLE_SSE42=1"
 
 PACKAGECONFIG ??= "gapi python3 eigen jpeg png tiff v4l libv4l gstreamer samples tbb gphoto2 \
     ${@bb.utils.contains("DISTRO_FEATURES", "x11", "gtk", "", d)} \