diff --git a/meta-oe/recipes-support/itstool/itstool/0001-Don-t-use-build-time-hardcoded-python-binary-path.patch b/meta-oe/recipes-support/itstool/itstool/0001-Don-t-use-build-time-hardcoded-python-binary-path.patch
new file mode 100644
index 0000000000..b91105330c
--- /dev/null
+++ b/meta-oe/recipes-support/itstool/itstool/0001-Don-t-use-build-time-hardcoded-python-binary-path.patch
@@ -0,0 +1,29 @@
+From cd9b56224895576125e91cca317ace8a80f3eb77 Mon Sep 17 00:00:00 2001
+From: Piotr Tworek <tworaz@tworaz.net>
+Date: Sat, 27 Jul 2019 10:19:11 +0200
+Subject: [PATCH] Don't use build time hardcoded python binary path.
+
+This path obviously won't work on target since they refer to build
+machine directory structure. Native builds will also fail if local.conf
+has INHERIT+=rm_work. Instread of hardcoding path to python binary use
+whatever is found in PATH first. This should also allow the tool to use
+python3 binary provided in recipe-sysroot-native.
+
+Upstream-Status: Inappropriate [OE specific]
+---
+ itstool.in | 2 +-
+ 1 file changed, 1 insertion(+), 1 deletion(-)
+
+diff --git a/itstool.in b/itstool.in
+index b3c0033..7df2476 100755
+--- a/itstool.in
++++ b/itstool.in
+@@ -1,4 +1,4 @@
+-#!@PYTHON@ -s
++#!/usr/bin/env -S python3 -s
+ #
+ # Copyright (c) 2010-2018 Shaun McCance <shaunm@gnome.org>
+ #
+--
+2.21.0
+
diff --git a/meta-oe/recipes-support/itstool/itstool_2.0.5.bb b/meta-oe/recipes-support/itstool/itstool_2.0.5.bb
index a0af44a71f..2e7e8f1941 100644
--- a/meta-oe/recipes-support/itstool/itstool_2.0.5.bb
+++ b/meta-oe/recipes-support/itstool/itstool_2.0.5.bb
@@ -7,15 +7,11 @@ inherit autotools python3native
 
 DEPENDS = "libxml2-native"
 
-SRC_URI = "http://files.itstool.org/${BPN}/${BPN}-${PV}.tar.bz2"
+SRC_URI = "http://files.itstool.org/${BPN}/${BPN}-${PV}.tar.bz2 \
+           file://0001-Don-t-use-build-time-hardcoded-python-binary-path.patch"
 SRC_URI[md5sum] = "655c6f78fc64faee45adcc45ccc5a57e"
 SRC_URI[sha256sum] = "100506f8df62cca6225ec3e631a8237e9c04650c77495af4919ac6a100d4b308"
 
-do_install_append() {
-    # fix shebang of main script
-    sed -i 's:^#!${WORKDIR}.*${PYTHON_PN} -s:#!${bindir_native}/${PYTHON_PN} -s:' ${D}${bindir}/itstool
-}
-
 BBCLASSEXTEND = "native"
 
 RDEPENDS_${PN} += "libxml2-python"