diff --git a/meta/recipes-core/musl/musl.inc b/meta/recipes-core/musl/musl.inc
index 5e6cd01fda..276b00fdc4 100644
--- a/meta/recipes-core/musl/musl.inc
+++ b/meta/recipes-core/musl/musl.inc
@@ -24,3 +24,6 @@ FILES_SOLIBSDEV = ""
 FILES_${PN} += "${libdir}/lib*${SOLIBSDEV}"
 INSANE_SKIP_${PN} = "dev-so"
 
+# Doesn't compile in MIPS16e mode due to use of hand-written
+# assembly
+MIPS_INSTRUCTION_SET = "mips"